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Clodronate Liposomes Improve Metabolic Profile and Reduce Visceral Adipose Macrophage Content in Diet-Induced Obese Mice
BACKGROUND: Obesity-related adipose inflammation has been thought to be a causal factor for the development of insulin resistance and type 2 diabetes. Infiltrated macrophages in adipose tissue of obese animals and humans are an important source for inflammatory cytokines. Clodronate liposomes can ab...
Autores principales: | Feng, Bin, Jiao, Ping, Nie, Yaohui, Kim, Thomas, Jun, Dale, van Rooijen, Nico, Yang, Zaiqing, Xu, Haiyan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3171445/ https://www.ncbi.nlm.nih.gov/pubmed/21931688 http://dx.doi.org/10.1371/journal.pone.0024358 |
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