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Resveratrol Suppresses Constitutive Activation of AKT via Generation of ROS and Induces Apoptosis in Diffuse Large B Cell Lymphoma Cell Lines

BACKGROUND: We have recently shown that deregulation PI3-kinase/AKT survival pathway plays an important role in pathogenesis of diffuse large B cell lymphoma (DLBCL). In an attempt to identify newer therapeutic agents, we investigated the role of Resveratrol (trans-3,4′, 5-trihydroxystilbene), a nat...

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Detalles Bibliográficos
Autores principales:	Hussain, Azhar R., Uddin, Shahab, Bu, Rong, Khan, Omar S., Ahmed, Saeeda O., Ahmed, Maqbool, Al-Kuraya, Khawla S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3171480/ https://www.ncbi.nlm.nih.gov/pubmed/21931821 http://dx.doi.org/10.1371/journal.pone.0024703

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