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Complex SUMO-1 Regulation of Cardiac Transcription Factor Nkx2-5

Reversible post-translational protein modifications such as SUMOylation add complexity to cardiac transcriptional regulation. The homeodomain transcription factor Nkx2-5/Csx is essential for heart specification and morphogenesis. It has been previously suggested that SUMOylation of lysine 51 (K51) o...

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Detalles Bibliográficos
Autores principales:	Costa, Mauro W., Lee, Stella, Furtado, Milena B., Xin, Li, Sparrow, Duncan B., Martinez, Camila G., Dunwoodie, Sally L., Kurtenbach, Eleonora, Mohun, Tim, Rosenthal, Nadia, Harvey, Richard P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3171482/ https://www.ncbi.nlm.nih.gov/pubmed/21931855 http://dx.doi.org/10.1371/journal.pone.0024812

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