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Understanding the limitations of radiation-induced cell cycle checkpoints

The DNA damage response pathways involve processes of double-strand break (DSB) repair and cell cycle checkpoint control to prevent or limit entry into S phase or mitosis in the presence of unrepaired damage. Checkpoints can function to permanently remove damaged cells from the actively proliferatin...

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Detalles Bibliográficos
Autores principales:	Deckbar, Dorothee, Jeggo, Penny A, Lobrich, Markus
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Informa Healthcare 2011
Materias:	Review Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3171706/ https://www.ncbi.nlm.nih.gov/pubmed/21524151 http://dx.doi.org/10.3109/10409238.2011.575764

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