The Role of Bile Acid Excretion in Atherosclerotic Coronary Artery Disease

The impact of cholesterol and different classes of lipoproteins on the development of coronary artery disease (CAD) has been investigated in extensively during the past 50 years. The cholesterol metabolism is dependent on numerous factors, including dietary fat, fractional absorption of dietary chol...

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Autores principales: Charach, Gideon, Rabinovich, Alexander, Argov, Ori, Weintraub, Moshe, Rabinovich, Pavel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3171758/
https://www.ncbi.nlm.nih.gov/pubmed/21918722
http://dx.doi.org/10.1155/2012/949672
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author Charach, Gideon
Rabinovich, Alexander
Argov, Ori
Weintraub, Moshe
Rabinovich, Pavel
author_facet Charach, Gideon
Rabinovich, Alexander
Argov, Ori
Weintraub, Moshe
Rabinovich, Pavel
author_sort Charach, Gideon
collection PubMed
description The impact of cholesterol and different classes of lipoproteins on the development of coronary artery disease (CAD) has been investigated in extensively during the past 50 years. The cholesterol metabolism is dependent on numerous factors, including dietary fat, fractional absorption of dietary cholesterol, tissue stores of cholesterol, endogenous cholesterol synthesis, and fecal bile excretion. Several studies showed significantly lower amounts of bile acid secretion in adult patients with CAD compared to non-CAD patients. Could it be that the inability to efficiently excrete bile acids may lead to CAD development?
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spelling pubmed-31717582011-09-14 The Role of Bile Acid Excretion in Atherosclerotic Coronary Artery Disease Charach, Gideon Rabinovich, Alexander Argov, Ori Weintraub, Moshe Rabinovich, Pavel Int J Vasc Med Review Article The impact of cholesterol and different classes of lipoproteins on the development of coronary artery disease (CAD) has been investigated in extensively during the past 50 years. The cholesterol metabolism is dependent on numerous factors, including dietary fat, fractional absorption of dietary cholesterol, tissue stores of cholesterol, endogenous cholesterol synthesis, and fecal bile excretion. Several studies showed significantly lower amounts of bile acid secretion in adult patients with CAD compared to non-CAD patients. Could it be that the inability to efficiently excrete bile acids may lead to CAD development? Hindawi Publishing Corporation 2012 2011-09-12 /pmc/articles/PMC3171758/ /pubmed/21918722 http://dx.doi.org/10.1155/2012/949672 Text en Copyright © 2012 Gideon Charach et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Charach, Gideon
Rabinovich, Alexander
Argov, Ori
Weintraub, Moshe
Rabinovich, Pavel
The Role of Bile Acid Excretion in Atherosclerotic Coronary Artery Disease
title The Role of Bile Acid Excretion in Atherosclerotic Coronary Artery Disease
title_full The Role of Bile Acid Excretion in Atherosclerotic Coronary Artery Disease
title_fullStr The Role of Bile Acid Excretion in Atherosclerotic Coronary Artery Disease
title_full_unstemmed The Role of Bile Acid Excretion in Atherosclerotic Coronary Artery Disease
title_short The Role of Bile Acid Excretion in Atherosclerotic Coronary Artery Disease
title_sort role of bile acid excretion in atherosclerotic coronary artery disease
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3171758/
https://www.ncbi.nlm.nih.gov/pubmed/21918722
http://dx.doi.org/10.1155/2012/949672
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