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Antimicrobial Actions of Reactive Oxygen Species

Everything should be as simple as it can be, but not simpler. —Attributed to Albert Einstein (1) Reactive oxygen species (ROS) are produced by host phagocytes and exert antimicrobial actions against a broad range of pathogens. The observable antimicrobial actions of ROS are highly dependent on exper...

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Detalles Bibliográficos
Autor principal: Fang, Ferric C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Microbiology 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3171981/
https://www.ncbi.nlm.nih.gov/pubmed/21896680
http://dx.doi.org/10.1128/mBio.00141-11
Descripción
Sumario:Everything should be as simple as it can be, but not simpler. —Attributed to Albert Einstein (1) Reactive oxygen species (ROS) are produced by host phagocytes and exert antimicrobial actions against a broad range of pathogens. The observable antimicrobial actions of ROS are highly dependent on experimental conditions. This perspective reviews recent controversies regarding ROS in Salmonella-phagocyte interactions and attempts to reconcile conflicting observations from different laboratories.