INITIAL RESPONSE TO ECT AS A PREDICTOR OF OUTCOME IN ENDOGENOUS DEPRESSION

In a double-blind, prospective study, 29 patients with endogenous depression were treated with electroconvulsive therapy (ECT). The degree of attenuation in Hamilton Rating Scale for Depression scores after the first ECT was compared between ECT responders and non-responders at the end of the treatm...

Descripción completa

Detalles Bibliográficos
Autores principales: Andrade, Chittaranjan, Gangadhar, B.N., Vythilingam, Meena, Channabasavanna, S.M., Pradhan, N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications 1989
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3172016/
https://www.ncbi.nlm.nih.gov/pubmed/21927403
_version_ 1782211815482064896
author Andrade, Chittaranjan
Gangadhar, B.N.
Vythilingam, Meena
Channabasavanna, S.M.
Pradhan, N.
author_facet Andrade, Chittaranjan
Gangadhar, B.N.
Vythilingam, Meena
Channabasavanna, S.M.
Pradhan, N.
author_sort Andrade, Chittaranjan
collection PubMed
description In a double-blind, prospective study, 29 patients with endogenous depression were treated with electroconvulsive therapy (ECT). The degree of attenuation in Hamilton Rating Scale for Depression scores after the first ECT was compared between ECT responders and non-responders at the end of the treatment course; a significant difference was obtained, indicating higher initial response in ECT responders. It is therefore suggested that response to a single trial ECT may form the basis for prediction of response of endogenous depression to a course of ECT. An operationalization of this concept is proposed, its sensitivity and specificity calculated, and its implications discussed.
format Online
Article
Text
id pubmed-3172016
institution National Center for Biotechnology Information
language English
publishDate 1989
publisher Medknow Publications
record_format MEDLINE/PubMed
spelling pubmed-31720162011-09-16 INITIAL RESPONSE TO ECT AS A PREDICTOR OF OUTCOME IN ENDOGENOUS DEPRESSION Andrade, Chittaranjan Gangadhar, B.N. Vythilingam, Meena Channabasavanna, S.M. Pradhan, N. Indian J Psychiatry Original Article In a double-blind, prospective study, 29 patients with endogenous depression were treated with electroconvulsive therapy (ECT). The degree of attenuation in Hamilton Rating Scale for Depression scores after the first ECT was compared between ECT responders and non-responders at the end of the treatment course; a significant difference was obtained, indicating higher initial response in ECT responders. It is therefore suggested that response to a single trial ECT may form the basis for prediction of response of endogenous depression to a course of ECT. An operationalization of this concept is proposed, its sensitivity and specificity calculated, and its implications discussed. Medknow Publications 1989 /pmc/articles/PMC3172016/ /pubmed/21927403 Text en Copyright: © Indian Journal of Psychiatry http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Andrade, Chittaranjan
Gangadhar, B.N.
Vythilingam, Meena
Channabasavanna, S.M.
Pradhan, N.
INITIAL RESPONSE TO ECT AS A PREDICTOR OF OUTCOME IN ENDOGENOUS DEPRESSION
title INITIAL RESPONSE TO ECT AS A PREDICTOR OF OUTCOME IN ENDOGENOUS DEPRESSION
title_full INITIAL RESPONSE TO ECT AS A PREDICTOR OF OUTCOME IN ENDOGENOUS DEPRESSION
title_fullStr INITIAL RESPONSE TO ECT AS A PREDICTOR OF OUTCOME IN ENDOGENOUS DEPRESSION
title_full_unstemmed INITIAL RESPONSE TO ECT AS A PREDICTOR OF OUTCOME IN ENDOGENOUS DEPRESSION
title_short INITIAL RESPONSE TO ECT AS A PREDICTOR OF OUTCOME IN ENDOGENOUS DEPRESSION
title_sort initial response to ect as a predictor of outcome in endogenous depression
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3172016/
https://www.ncbi.nlm.nih.gov/pubmed/21927403
work_keys_str_mv AT andradechittaranjan initialresponsetoectasapredictorofoutcomeinendogenousdepression
AT gangadharbn initialresponsetoectasapredictorofoutcomeinendogenousdepression
AT vythilingammeena initialresponsetoectasapredictorofoutcomeinendogenousdepression
AT channabasavannasm initialresponsetoectasapredictorofoutcomeinendogenousdepression
AT pradhann initialresponsetoectasapredictorofoutcomeinendogenousdepression

Ejemplares similares