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Replication protein A promotes 5′→3′ end processing during homology-dependent DNA double-strand break repair

Replication protein A (RPA), the eukaryotic single-strand deoxyribonucleic acid (DNA [ss-DNA])–binding protein, is involved in DNA replication, nucleotide damage repair, mismatch repair, and DNA damage checkpoint response, but its function in DNA double-strand break (DSB) repair is poorly understood...

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Detalles Bibliográficos
Autores principales: Yan, Hong, Toczylowski, Thomas, McCane, Jill, Chen, Chinyi, Liao, Shuren
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3172182/
https://www.ncbi.nlm.nih.gov/pubmed/21263027
http://dx.doi.org/10.1083/jcb.201005110