CD81 Is Essential for the Re-entry of Hematopoietic Stem Cells to Quiescence following Stress-Induced Proliferation Via Deactivation of the Akt Pathway

The regulatory mechanisms governing the cell cycle progression of hematopoietic stem cells (HSCs) are well characterized, but those responsible for the return of proliferating HSCs to a quiescent state remain largely unknown. Here, we present evidence that CD81, a tetraspanin molecule acutely respon...

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Detalles Bibliográficos
Autores principales: Lin, Kuanyin K., Rossi, Lara, Boles, Nathan C., Hall, Brian E., George, Thaddeus C., Goodell, Margaret A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3172193/
https://www.ncbi.nlm.nih.gov/pubmed/21931533
http://dx.doi.org/10.1371/journal.pbio.1001148

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