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Luciferase-Expressing Leishmania infantum Allows the Monitoring of Amastigote Population Size, In Vivo, Ex Vivo and In Vitro

Here we engineered transgenic Leishmania infantum that express luciferase, the objectives being to more easily monitor in real time their establishment either in BALB/c mice—the liver and spleen being mainly studied—or in vitro. Whatever stationary phase L. infantum promastigotes population—wild typ...

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Detalles Bibliográficos
Autores principales: Michel, Grégory, Ferrua, Bernard, Lang, Thierry, Maddugoda, Madhavi P., Munro, Patrick, Pomares, Christelle, Lemichez, Emmanuel, Marty, Pierre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3172198/
https://www.ncbi.nlm.nih.gov/pubmed/21931877
http://dx.doi.org/10.1371/journal.pntd.0001323