Myostatin Is Elevated in Congenital Heart Disease and After Mechanical Unloading

BACKGROUND: Myostatin is a negative regulator of skeletal muscle mass whose activity is upregulated in adult heart failure (HF); however, its role in congenital heart disease (CHD) is unknown. METHODS: We studied myostatin and IGF-1 expression via Western blot in cardiac tissue at varying degrees of...

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Detalles Bibliográficos
Autores principales: Bish, Lawrence T., George, Isaac, Maybaum, Simon, Yang, Jonathan, Chen, Jonathan M., Sweeney, H. Lee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3172210/
https://www.ncbi.nlm.nih.gov/pubmed/21931616
http://dx.doi.org/10.1371/journal.pone.0023818

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