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Triptolide (TPL) Inhibits Global Transcription by Inducing Proteasome-Dependent Degradation of RNA Polymerase II (Pol II)

Triptolide (TPL), a key biologically active component of the Chinese medicinal herb Tripterygium wilfordii Hook. f., has potent anti-inflammation and anti-cancer activities. Its anti-proliferative and pro-apoptotic effects have been reported to be related to the inhibition of Nuclear Factor κB (NF-κ...

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Detalles Bibliográficos
Autores principales:	Wang, Ying, Lu, Jin-jian, He, Li, Yu, Qiang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3172214/ https://www.ncbi.nlm.nih.gov/pubmed/21931633 http://dx.doi.org/10.1371/journal.pone.0023993

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