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Pdx1 and Ngn3 Overexpression Enhances Pancreatic Differentiation of Mouse ES Cell-Derived Endoderm Population

In order to define the molecular mechanisms regulating the specification and differentiation of pancreatic β-islet cells, we investigated the effect of upregulating Pdx1 and Ngn3 during the differentiation of the β-islet-like cells from murine embryonic stem (ES) cell-derived activin induced-endoder...

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Detalles Bibliográficos
Autores principales:	Kubo, Atsushi, Stull, Robert, Takeuchi, Mitsuaki, Bonham, Kristina, Gouon-Evans, Valerie, Sho, Masayuki, Iwano, Masayuki, Saito, Yoshihiko, Keller, Gordon, Snodgrass, Ralph
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3172220/ https://www.ncbi.nlm.nih.gov/pubmed/21931641 http://dx.doi.org/10.1371/journal.pone.0024058

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