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Suppression of Breast Tumor Growth and Metastasis by an Engineered Transcription Factor

Maspin is a tumor and metastasis suppressor playing an essential role as gatekeeper of tumor progression. It is highly expressed in epithelial cells but is silenced in the onset of metastatic disease by epigenetic mechanisms. Reprogramming of Maspin epigenetic silencing offers a therapeutic potentia...

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Detalles Bibliográficos
Autores principales:	Beltran, Adriana S., Russo, Angela, Lara, Haydee, Fan, Cheng, Lizardi, Paul M., Blancafort, Pilar
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3172243/ https://www.ncbi.nlm.nih.gov/pubmed/21931769 http://dx.doi.org/10.1371/journal.pone.0024595

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