Novel Molecular and Computational Methods Improve the Accuracy of Insertion Site Analysis in Sleeping Beauty-Induced Tumors

The recent development of the Sleeping Beauty (SB) system has led to the development of novel mouse models of cancer. Unlike spontaneous models, SB causes cancer through the action of mutagenic transposons that are mobilized in the genomes of somatic cells to induce mutations in cancer genes. While...

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Detalles Bibliográficos
Autores principales: Brett, Benjamin T., Berquam-Vrieze, Katherine E., Nannapaneni, Kishore, Huang, Jian, Scheetz, Todd E., Dupuy, Adam J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3172244/
https://www.ncbi.nlm.nih.gov/pubmed/21931803
http://dx.doi.org/10.1371/journal.pone.0024668

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3172244/
https://www.ncbi.nlm.nih.gov/pubmed/21931803
http://dx.doi.org/10.1371/journal.pone.0024668

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