IL28B, HLA-C, and KIR Variants Additively Predict Response to Therapy in Chronic Hepatitis C Virus Infection in a European Cohort: A Cross-Sectional Study

BACKGROUND: To date, drug response genes have not proved as useful in clinical practice as was anticipated at the start of the genomic era. An exception is in the treatment of chronic hepatitis C virus (HCV) genotype 1 infection with pegylated interferon-alpha and ribavirin (PegIFN/R). Viral clearan...

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Detalles Bibliográficos
Autores principales: Suppiah, Vijayaprakash, Gaudieri, Silvana, Armstrong, Nicola J., O'Connor, Kate S., Berg, Thomas, Weltman, Martin, Abate, Maria Lorena, Spengler, Ulrich, Bassendine, Margaret, Dore, Gregory J., Irving, William L., Powell, Elizabeth, Hellard, Margaret, Riordan, Stephen, Matthews, Gail, Sheridan, David, Nattermann, Jacob, Smedile, Antonina, Müller, Tobias, Hammond, Emma, Dunn, David, Negro, Francesco, Bochud, Pierre-Yves, Mallal, Simon, Ahlenstiel, Golo, Stewart, Graeme J., George, Jacob, Booth, David R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3172251/
https://www.ncbi.nlm.nih.gov/pubmed/21931540
http://dx.doi.org/10.1371/journal.pmed.1001092

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