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An active kinase domain is required for retention of PKCθ at the T cell immunological synapse

Protein kinase Cθ (PKCθ) is a serine/threonine kinase that plays an essential role in antigen-regulated responses of T lymphocytes. Upon antigen stimulation, PKCθ is rapidly recruited to the immunological synapse (IS), the region of contact between the T cell and antigen-presenting cell. This behavi...

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Detalles Bibliográficos
Autores principales:	Cartwright, Natalia G., Kashyap, Anuj K., Schaefer, Brian C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The American Society for Cell Biology 2011
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3172272/ https://www.ncbi.nlm.nih.gov/pubmed/21795397 http://dx.doi.org/10.1091/mbc.E10-11-0916

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