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Membrane aberrancy and unfolded proteins activate the endoplasmic reticulum stress sensor Ire1 in different ways

Eukaryotic cells activate the unfolded-protein response (UPR) upon endoplasmic reticulum (ER) stress, where the stress is assumed to be the accumulation of unfolded proteins in the ER. Consistent with previous in vitro studies of the ER-luminal domain of the mutant UPR initiator Ire1, our study show...

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Detalles Bibliográficos
Autores principales:	Promlek, Thanyarat, Ishiwata-Kimata, Yuki, Shido, Masahiro, Sakuramoto, Mitsuru, Kohno, Kenji, Kimata, Yukio
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The American Society for Cell Biology 2011
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3172275/ https://www.ncbi.nlm.nih.gov/pubmed/21775630 http://dx.doi.org/10.1091/mbc.E11-04-0295

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