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Styryl-Based and Tricyclic Compounds as Potential Anti-Prion Agents
Prion diseases currently have no effective therapy. These illnesses affect both animal and human populations, and are characterized by the conformational change of a normal self protein PrP(C) (C for cellular) to a pathological and infectious conformer, PrP(Sc) (Sc for scrapie). We used a well chara...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3172287/ https://www.ncbi.nlm.nih.gov/pubmed/21931860 http://dx.doi.org/10.1371/journal.pone.0024844 |