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CDinFusion – Submission-Ready, On-Line Integration of Sequence and Contextual Data

State of the art (DNA) sequencing methods applied in “Omics” studies grant insight into the ‘blueprints’ of organisms from all domains of life. Sequencing is carried out around the globe and the data is submitted to the public repositories of the International Nucleotide Sequence Database Collaborat...

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Autores principales: Hankeln, Wolfgang, Wendel, Norma Johanna, Gerken, Jan, Waldmann, Jost, Buttigieg, Pier Luigi, Kostadinov, Ivaylo, Kottmann, Renzo, Yilmaz, Pelin, Glöckner, Frank Oliver
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3172294/
https://www.ncbi.nlm.nih.gov/pubmed/21935468
http://dx.doi.org/10.1371/journal.pone.0024797
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author Hankeln, Wolfgang
Wendel, Norma Johanna
Gerken, Jan
Waldmann, Jost
Buttigieg, Pier Luigi
Kostadinov, Ivaylo
Kottmann, Renzo
Yilmaz, Pelin
Glöckner, Frank Oliver
author_facet Hankeln, Wolfgang
Wendel, Norma Johanna
Gerken, Jan
Waldmann, Jost
Buttigieg, Pier Luigi
Kostadinov, Ivaylo
Kottmann, Renzo
Yilmaz, Pelin
Glöckner, Frank Oliver
author_sort Hankeln, Wolfgang
collection PubMed
description State of the art (DNA) sequencing methods applied in “Omics” studies grant insight into the ‘blueprints’ of organisms from all domains of life. Sequencing is carried out around the globe and the data is submitted to the public repositories of the International Nucleotide Sequence Database Collaboration. However, the context in which these studies are conducted often gets lost, because experimental data, as well as information about the environment are rarely submitted along with the sequence data. If these contextual or metadata are missing, key opportunities of comparison and analysis across studies and habitats are hampered or even impossible. To address this problem, the Genomic Standards Consortium (GSC) promotes checklists and standards to better describe our sequence data collection and to promote the capturing, exchange and integration of sequence data with contextual data. In a recent community effort the GSC has developed a series of recommendations for contextual data that should be submitted along with sequence data. To support the scientific community to significantly enhance the quality and quantity of contextual data in the public sequence data repositories, specialized software tools are needed. In this work we present CDinFusion, a web-based tool to integrate contextual and sequence data in (Multi)FASTA format prior to submission. The tool is open source and available under the Lesser GNU Public License 3. A public installation is hosted and maintained at the Max Planck Institute for Marine Microbiology at http://www.megx.net/cdinfusion. The tool may also be installed locally using the open source code available at http://code.google.com/p/cdinfusion.
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spelling pubmed-31722942011-09-20 CDinFusion – Submission-Ready, On-Line Integration of Sequence and Contextual Data Hankeln, Wolfgang Wendel, Norma Johanna Gerken, Jan Waldmann, Jost Buttigieg, Pier Luigi Kostadinov, Ivaylo Kottmann, Renzo Yilmaz, Pelin Glöckner, Frank Oliver PLoS One Research Article State of the art (DNA) sequencing methods applied in “Omics” studies grant insight into the ‘blueprints’ of organisms from all domains of life. Sequencing is carried out around the globe and the data is submitted to the public repositories of the International Nucleotide Sequence Database Collaboration. However, the context in which these studies are conducted often gets lost, because experimental data, as well as information about the environment are rarely submitted along with the sequence data. If these contextual or metadata are missing, key opportunities of comparison and analysis across studies and habitats are hampered or even impossible. To address this problem, the Genomic Standards Consortium (GSC) promotes checklists and standards to better describe our sequence data collection and to promote the capturing, exchange and integration of sequence data with contextual data. In a recent community effort the GSC has developed a series of recommendations for contextual data that should be submitted along with sequence data. To support the scientific community to significantly enhance the quality and quantity of contextual data in the public sequence data repositories, specialized software tools are needed. In this work we present CDinFusion, a web-based tool to integrate contextual and sequence data in (Multi)FASTA format prior to submission. The tool is open source and available under the Lesser GNU Public License 3. A public installation is hosted and maintained at the Max Planck Institute for Marine Microbiology at http://www.megx.net/cdinfusion. The tool may also be installed locally using the open source code available at http://code.google.com/p/cdinfusion. Public Library of Science 2011-09-13 /pmc/articles/PMC3172294/ /pubmed/21935468 http://dx.doi.org/10.1371/journal.pone.0024797 Text en Hankeln et al. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.
spellingShingle Research Article
Hankeln, Wolfgang
Wendel, Norma Johanna
Gerken, Jan
Waldmann, Jost
Buttigieg, Pier Luigi
Kostadinov, Ivaylo
Kottmann, Renzo
Yilmaz, Pelin
Glöckner, Frank Oliver
CDinFusion – Submission-Ready, On-Line Integration of Sequence and Contextual Data
title CDinFusion – Submission-Ready, On-Line Integration of Sequence and Contextual Data
title_full CDinFusion – Submission-Ready, On-Line Integration of Sequence and Contextual Data
title_fullStr CDinFusion – Submission-Ready, On-Line Integration of Sequence and Contextual Data
title_full_unstemmed CDinFusion – Submission-Ready, On-Line Integration of Sequence and Contextual Data
title_short CDinFusion – Submission-Ready, On-Line Integration of Sequence and Contextual Data
title_sort cdinfusion – submission-ready, on-line integration of sequence and contextual data
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3172294/
https://www.ncbi.nlm.nih.gov/pubmed/21935468
http://dx.doi.org/10.1371/journal.pone.0024797
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