Increased in vivo release of neuropeptide S in the amygdala of freely moving rats after local depolarisation and emotional stress

Intracerebral microdialysis in conjunction with a highly sensitive radioimmunoassay was used to study the in vivo release of neuropeptide S (NPS) within the amygdala of freely moving rats. NPS was consistently detected in basolateral amygdala dialysates and the release considerably enhanced in respo...

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Detalles Bibliográficos
Autores principales: Ebner, Karl, Rjabokon, Alesja, Pape, Hans-Christian, Singewald, Nicolas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Vienna 2011
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3172411/
https://www.ncbi.nlm.nih.gov/pubmed/21861171
http://dx.doi.org/10.1007/s00726-011-1058-0
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author Ebner, Karl
Rjabokon, Alesja
Pape, Hans-Christian
Singewald, Nicolas
author_facet Ebner, Karl
Rjabokon, Alesja
Pape, Hans-Christian
Singewald, Nicolas
author_sort Ebner, Karl
collection PubMed
description Intracerebral microdialysis in conjunction with a highly sensitive radioimmunoassay was used to study the in vivo release of neuropeptide S (NPS) within the amygdala of freely moving rats. NPS was consistently detected in basolateral amygdala dialysates and the release considerably enhanced in response to local depolarisation as well as exposure to forced swim stress. Thus, our data demonstrate for the first time emotional stress-induced release of NPS in the amygdala supporting a functional role of endogenous NPS in stress/anxiety-related phenomena.
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spelling pubmed-31724112011-09-26 Increased in vivo release of neuropeptide S in the amygdala of freely moving rats after local depolarisation and emotional stress Ebner, Karl Rjabokon, Alesja Pape, Hans-Christian Singewald, Nicolas Amino Acids Short Communication Intracerebral microdialysis in conjunction with a highly sensitive radioimmunoassay was used to study the in vivo release of neuropeptide S (NPS) within the amygdala of freely moving rats. NPS was consistently detected in basolateral amygdala dialysates and the release considerably enhanced in response to local depolarisation as well as exposure to forced swim stress. Thus, our data demonstrate for the first time emotional stress-induced release of NPS in the amygdala supporting a functional role of endogenous NPS in stress/anxiety-related phenomena. Springer Vienna 2011-08-23 2011 /pmc/articles/PMC3172411/ /pubmed/21861171 http://dx.doi.org/10.1007/s00726-011-1058-0 Text en © The Author(s) 2011 https://creativecommons.org/licenses/by-nc/4.0/ This article is distributed under the terms of the Creative Commons Attribution Noncommercial License which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author(s) and source are credited.
spellingShingle Short Communication
Ebner, Karl
Rjabokon, Alesja
Pape, Hans-Christian
Singewald, Nicolas
Increased in vivo release of neuropeptide S in the amygdala of freely moving rats after local depolarisation and emotional stress
title Increased in vivo release of neuropeptide S in the amygdala of freely moving rats after local depolarisation and emotional stress
title_full Increased in vivo release of neuropeptide S in the amygdala of freely moving rats after local depolarisation and emotional stress
title_fullStr Increased in vivo release of neuropeptide S in the amygdala of freely moving rats after local depolarisation and emotional stress
title_full_unstemmed Increased in vivo release of neuropeptide S in the amygdala of freely moving rats after local depolarisation and emotional stress
title_short Increased in vivo release of neuropeptide S in the amygdala of freely moving rats after local depolarisation and emotional stress
title_sort increased in vivo release of neuropeptide s in the amygdala of freely moving rats after local depolarisation and emotional stress
topic Short Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3172411/
https://www.ncbi.nlm.nih.gov/pubmed/21861171
http://dx.doi.org/10.1007/s00726-011-1058-0
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AT papehanschristian increasedinvivoreleaseofneuropeptidesintheamygdalaoffreelymovingratsafterlocaldepolarisationandemotionalstress
AT singewaldnicolas increasedinvivoreleaseofneuropeptidesintheamygdalaoffreelymovingratsafterlocaldepolarisationandemotionalstress

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