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G-Quadruplexes: From Guanine Gels to Chemotherapeutics
G-quartets are square planar arrangements of four guanine bases, which can form extraordinarily stable stacks when present in nucleic acid sequences. Such G-quadruplex structures were long regarded as an in vitro phenomenon, but the widespread presence of suitable sequences in genomes and the identi...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Humana Press Inc
2011
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3172417/ https://www.ncbi.nlm.nih.gov/pubmed/21416200 http://dx.doi.org/10.1007/s12033-011-9395-5 |