Protein surface recognition using geometrically pure Ru(ii) tris(bipyridine) derivatives

This manuscript illustrates that the geometric arrangement of protein-binding groups around a ruthenium(ii) core leads to dramatic differences in cytochrome c (cyt c) binding highlighting that it is possible to define synthetic receptors with shape complementarity to protein surfaces.

Detalles Bibliográficos
Autores principales: Filby, Maria H., Muldoon, James, Dabb, Serin, Fletcher, Nicholas C., Ashcroft, Alison E., Wilson, Andrew J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2011
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3172587/
https://www.ncbi.nlm.nih.gov/pubmed/21103575
http://dx.doi.org/10.1039/c0cc04754f
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author Filby, Maria H.
Muldoon, James
Dabb, Serin
Fletcher, Nicholas C.
Ashcroft, Alison E.
Wilson, Andrew J.
author_facet Filby, Maria H.
Muldoon, James
Dabb, Serin
Fletcher, Nicholas C.
Ashcroft, Alison E.
Wilson, Andrew J.
author_sort Filby, Maria H.
collection PubMed
description This manuscript illustrates that the geometric arrangement of protein-binding groups around a ruthenium(ii) core leads to dramatic differences in cytochrome c (cyt c) binding highlighting that it is possible to define synthetic receptors with shape complementarity to protein surfaces.
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spelling pubmed-31725872011-09-26 Protein surface recognition using geometrically pure Ru(ii) tris(bipyridine) derivatives Filby, Maria H. Muldoon, James Dabb, Serin Fletcher, Nicholas C. Ashcroft, Alison E. Wilson, Andrew J. Chem Commun (Camb) Chemistry This manuscript illustrates that the geometric arrangement of protein-binding groups around a ruthenium(ii) core leads to dramatic differences in cytochrome c (cyt c) binding highlighting that it is possible to define synthetic receptors with shape complementarity to protein surfaces. Royal Society of Chemistry 2011-01-07 2010-11-23 /pmc/articles/PMC3172587/ /pubmed/21103575 http://dx.doi.org/10.1039/c0cc04754f Text en This journal is © The Royal Society of Chemistry 2010 http://creativecommons.org/licenses/by-nc/2.0/uk/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/2.0/uk/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Chemistry
Filby, Maria H.
Muldoon, James
Dabb, Serin
Fletcher, Nicholas C.
Ashcroft, Alison E.
Wilson, Andrew J.
Protein surface recognition using geometrically pure Ru(ii) tris(bipyridine) derivatives
title Protein surface recognition using geometrically pure Ru(ii) tris(bipyridine) derivatives
title_full Protein surface recognition using geometrically pure Ru(ii) tris(bipyridine) derivatives
title_fullStr Protein surface recognition using geometrically pure Ru(ii) tris(bipyridine) derivatives
title_full_unstemmed Protein surface recognition using geometrically pure Ru(ii) tris(bipyridine) derivatives
title_short Protein surface recognition using geometrically pure Ru(ii) tris(bipyridine) derivatives
title_sort protein surface recognition using geometrically pure ru(ii) tris(bipyridine) derivatives
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3172587/
https://www.ncbi.nlm.nih.gov/pubmed/21103575
http://dx.doi.org/10.1039/c0cc04754f
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