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Evolution of phage with chemically ambiguous proteomes
BACKGROUND: The widespread introduction of amino acid substitutions into organismal proteomes has occurred during natural evolution, but has been difficult to achieve by directed evolution. The adaptation of the translation apparatus represents one barrier, but the multiple mutations that may be req...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2003
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC317279/ https://www.ncbi.nlm.nih.gov/pubmed/14667253 http://dx.doi.org/10.1186/1471-2148-3-24 |