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EGFR gene amplification is related to adverse clinical outcomes in cervical squamous cell carcinoma, making the EGFR pathway a novel therapeutic target

BACKGROUND: The aim of this study was to investigate the patterns of epidermal growth factor receptor (EGFR) overexpression, EGFR gene amplification, and the presence of activating mutations in the tyrosine kinase domain of this gene in squamous cell carcinomas and adenocarcinomas/adenosquamous carc...

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Detalles Bibliográficos
Autores principales:	Iida, K, Nakayama, K, Rahman, M T, Rahman, M, Ishikawa, M, Katagiri, A, Yeasmin, S, Otsuki, Y, Kobayashi, H, Nakayama, S, Miyazaki, K
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2011
Materias:	Molecular Diagnostics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3172895/ https://www.ncbi.nlm.nih.gov/pubmed/21730982 http://dx.doi.org/10.1038/bjc.2011.222

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