Oncogenic AKTivation of translation as a therapeutic target

The AKT signalling pathway is a major regulator of protein synthesis that impinges on multiple cellular processes frequently altered in cancer, such as proliferation, cell growth, survival, and angiogenesis. AKT controls protein synthesis by regulating the multistep process of mRNA translation at ev...

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Detalles Bibliográficos
Autores principales: Hsieh, A C, Truitt, M L, Ruggero, D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2011
Materias:
Minireview
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3172900/
https://www.ncbi.nlm.nih.gov/pubmed/21772331
http://dx.doi.org/10.1038/bjc.2011.241

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3172900/
https://www.ncbi.nlm.nih.gov/pubmed/21772331
http://dx.doi.org/10.1038/bjc.2011.241

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