A novel mutation of the calcium sensing receptor gene is associated with chronic pancreatitis in a family with heterozygous SPINK1 mutations

BACKGROUND: The role of mutations in the serine protease inhibitor Kazal type 1 (SPINK1) gene in chronic pancreatitis is still a matter of debate. Active SPINK1 is thought to antagonize activated trypsin. Cases of SPINK1 mutations, especially N34S, have been reported in a subset of patients with idi...

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Detalles Bibliográficos
Autores principales: Felderbauer, Peter, Hoffmann, Peter, Einwächter, Henrik, Bulut, Kerem, Ansorge, Nikolaus, Schmitz, Frank, Schmidt, Wolfgang E
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2003
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC317302/
https://www.ncbi.nlm.nih.gov/pubmed/14641934
http://dx.doi.org/10.1186/1471-230X-3-34

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