Effects of CXCR4 siRNA/dextran-spermine nanoparticles on CXCR4 expression and serum LDH levels in a mouse model of colorectal cancer metastasis to the liver

Liver metastasis is the main cause of mortality related to colorectal cancer. CXCR4 is necessary for the outgrowth of colon cancer micrometastases. In oncology, it has been demonstrated that several human tumors release lactate dehydrogenase (LDH) into the circulation. CXCR4 gene expression and seru...

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Detalles Bibliográficos
Autores principales: Abedini, Fatemeh, Ismail, Maznah, Hosseinkhani, Hossein, Ibrahim, Tengku Azmi Tengku, Omar, Abdul Rahman, Chong, Pei Pei, Bejo, Mohd Hair, Domb, Abraham J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2011
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3173020/
https://www.ncbi.nlm.nih.gov/pubmed/21931504
http://dx.doi.org/10.2147/CMR.S11678

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