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Caspase-1 Promiscuity Is Counterbalanced by Rapid Inactivation of Processed Enzyme

Members of the caspase family of cysteine proteases coordinate the highly disparate processes of apoptosis and inflammation. However, although hundreds of substrates for the apoptosis effector caspases (caspase-3 and caspase-7) have been identified, only two confirmed substrates for the key inflamma...

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Detalles Bibliográficos
Autores principales: Walsh, John G., Logue, Susan E., Lüthi, Alexander U., Martin, Seamus J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3173193/
https://www.ncbi.nlm.nih.gov/pubmed/21757759
http://dx.doi.org/10.1074/jbc.M111.225862