Cargando…
Lectin Domains of Polypeptide GalNAc Transferases Exhibit Glycopeptide Binding Specificity
UDP-GalNAc:polypeptide α-N-acetylgalactosaminyltransferases (GalNAc-Ts) constitute a family of up to 20 transferases that initiate mucin-type O-glycosylation. The transferases are structurally composed of catalytic and lectin domains. Two modes have been identified for the selection of glycosylation...
Autores principales: | Pedersen, Johannes W., Bennett, Eric P., Schjoldager, Katrine T.-B. G., Meldal, Morten, Holmér, Andreas P., Blixt, Ola, Cló, Emiliano, Levery, Steven B., Clausen, Henrik, Wandall, Hans H. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2011
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3173194/ https://www.ncbi.nlm.nih.gov/pubmed/21768105 http://dx.doi.org/10.1074/jbc.M111.273722 |
Ejemplares similares
-
Cytokines Alter IgA1 O-Glycosylation by Dysregulating C1GalT1 and ST6GalNAc-II Enzymes
por: Suzuki, Hitoshi, et al.
Publicado: (2014) -
Structures of Complexes of a Metal-independent Glycosyltransferase GT6 from Bacteroides ovatus with UDP-N-Acetylgalactosamine (UDP-GalNAc) and Its Hydrolysis Products
por: Pham, Tram T. K., et al.
Publicado: (2014) -
The Early Metazoan Trichoplax adhaerens Possesses a Functional O-GlcNAc System
por: Selvan, Nithya, et al.
Publicado: (2015) -
The conserved threonine-rich region of the HCF-1(PRO) repeat activates promiscuous OGT:UDP-GlcNAc glycosylation and proteolysis activities
por: Kapuria, Vaibhav, et al.
Publicado: (2018) -
Binding of N-Acetylglucosamine (GlcNAc) β1–6-branched Oligosaccharide Acceptors to β4-Galactosyltransferase I Reveals a New Ligand Binding Mode
por: Ramakrishnan, Boopathy, et al.
Publicado: (2012)