Improvement of a Potential Anthrax Therapeutic by Computational Protein Design

Past anthrax attacks in the United States have highlighted the need for improved measures against bioweapons. The virulence of anthrax stems from the shielding properties of the Bacillus anthracis poly-γ-d-glutamic acid capsule. In the presence of excess CapD, a B. anthracis γ-glutamyl transpeptidas...

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Detalles Bibliográficos
Autores principales: Wu, Sean J., Eiben, Christopher B., Carra, John H., Huang, Ivan, Zong, David, Liu, Peixian, Wu, Cindy T., Nivala, Jeff, Dunbar, Josef, Huber, Tomas, Senft, Jeffrey, Schokman, Rowena, Smith, Matthew D., Mills, Jeremy H., Friedlander, Arthur M., Baker, David, Siegel, Justin B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2011
Materias:
Computational Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3173206/
https://www.ncbi.nlm.nih.gov/pubmed/21768086
http://dx.doi.org/10.1074/jbc.M111.251041

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