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NKAP is required for T cell maturation and acquisition of functional competency

Newly generated T cells are unable to respond to antigen/MHC. Rather, post-selection single-positive thymocytes must undergo T cell maturation to gain functional competency and enter the long-lived naive peripheral T cell pool. This process is poorly understood, as no gene specifically required for...

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Detalles Bibliográficos
Autores principales: Hsu, Fan-Chi, Pajerowski, Anthony G., Nelson-Holte, Molly, Sundsbak, Rhianna, Shapiro, Virginia Smith
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3173250/
https://www.ncbi.nlm.nih.gov/pubmed/21624937
http://dx.doi.org/10.1084/jem.20101874