Cargando…

Invariant NKT cells are required for airway inflammation induced by environmental antigens

Invariant NKT cells (iNKT cells) are a unique subset of T lymphocytes that rapidly carry out effector functions. In this study, we report that a majority of sterile house dust extracts (HDEs) tested contained antigens capable of activating mouse and human iNKT cells. HDEs had adjuvant-like propertie...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wingender, Gerhard, Rogers, Paul, Batzer, Glenda, Lee, Myung Steve, Bai, Dong, Pei, Bo, Khurana, Archana, Kronenberg, Mitchell, Horner, Anthony A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2011
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3173256/ https://www.ncbi.nlm.nih.gov/pubmed/21624935 http://dx.doi.org/10.1084/jem.20102229

Ejemplares similares

Improved Detection of Cytokines Produced by Invariant NKT Cells
por: Sag, Duygu, et al.
Publicado: (2017)

NKT10 cells: a novel iNKT cell subset
por: Wingender, Gerhard, et al.
Publicado: (2015)

Invariant NKT cells recognize glycolipids from pathogenic Gram-positive bacteria
por: Kinjo, Yuki, et al.
Publicado: (2011)

The Adaptor Protein AP-3 Is Required for CD1d-Mediated Antigen Presentation of Glycosphingolipids and Development of Vα14i NKT Cells
por: Elewaut, Dirk, et al.
Publicado: (2003)

Eomes transcription factor is required for the development and differentiation of invariant NKT cells
por: Shimizu, Kanako, et al.
Publicado: (2019)

Antigen specificity of invariant natural killer T-cells
por: Birkholz, Alysia M., et al.
Publicado: (2015)

Unique Interplay between Sugar and Lipid in Determining the Antigenic Potency of Bacterial Antigens for NKT Cells
por: Girardi, Enrico, et al.
Publicado: (2011)

Altered thymic differentiation and modulation of arthritis by invariant NKT cells expressing mutant ZAP70
por: Zhao, Meng, et al.
Publicado: (2018)

Vaccine Designs Utilizing Invariant NKT-Licensed Antigen-Presenting Cells Provide NKT or T Cell Help for B Cell Responses
por: Fujii, Shin-ichiro, et al.
Publicado: (2018)

Intracellular Bacterial Infection and Invariant NKT Cells
por: Emoto, Masashi, et al.
Publicado: (2009)

Invariant NKT cells: Killers and conspirators against cancer
por: Bassiri, Hamid, et al.
Publicado: (2013)

Activation of Invariant NKT Cells Exacerbates Experimental Visceral Leishmaniasis
por: Stanley, Amanda C., et al.
Publicado: (2008)

Invariant NKT Cells: Regulation and Function during Viral Infection
por: Juno, Jennifer A., et al.
Publicado: (2012)

Invariant NKT Cell Response to Dengue Virus Infection in Human
por: Matangkasombut, Ponpan, et al.
Publicado: (2014)

Invariant NKT Cells as Novel Targets for Immunotherapy in Solid Tumors
por: Pilones, Karsten A., et al.
Publicado: (2012)

Effects of Invariant NKT Cells on Parasite Infections and Hygiene Hypothesis
por: Yang, Jun-Qi, et al.
Publicado: (2016)

Novel Approaches to Exploiting Invariant NKT Cells in Cancer Immunotherapy
por: Wolf, Benjamin J., et al.
Publicado: (2018)

CD169(+) MACROPHAGES PRESENT LIPID ANTIGENS TO MEDIATE EARLY ACTIVATION OF INVARIANT NKT CELLS IN LYMPH NODES
por: Barral, Patricia, et al.
Publicado: (2010)

Mouse Invariant Monoclonal Antibody NKT14: A Novel Tool to Manipulate iNKT Cell Function In Vivo
por: Scheuplein, Felix, et al.
Publicado: (2015)

Transcriptome and chromatin landscape of iNKT cells are shaped by subset differentiation and antigen exposure
por: Murray, Mallory Paynich, et al.
Publicado: (2021)

Cutaneous Immunization Rapidly Activates Liver Invariant Vα14 NKT Cells Stimulating B-1 B Cells to Initiate T Cell Recruitment for Elicitation of Contact Sensitivity
por: Campos, Regis A., et al.
Publicado: (2003)

Invariant NKT Cells as Initiators, Licensors, and Facilitators of the Adaptive Immune Response
por: Stein-Streilein, Joan
Publicado: (2003)

Exploiting invariant NKT cells to promote T-cell responses to cancer vaccines
por: Hunn, Martin K., et al.
Publicado: (2013)

TIM-4 is expressed on invariant NKT cells but dispensable for their development and function
por: Zhang, Xilin, et al.
Publicado: (2016)

Invariant NKT Cells and Rheumatic Disease: Focus on Primary Sjogren Syndrome
por: Rizzo, Chiara, et al.
Publicado: (2019)

Invariant NKT cells metabolically adapt to the acute myeloid leukaemia environment
por: Stavrou, Victoria, et al.
Publicado: (2022)

Airborne lipid antigens mobilize resident intravascular NKT cells to induce allergic airway inflammation
por: Scanlon, Seth T., et al.
Publicado: (2011)

Mrp1 is involved in lipid presentation and iNKT cell activation by Streptococcus pneumoniae
por: Chandra, Shilpi, et al.
Publicado: (2018)

Immune cells and preterm labour: do invariant NKT cells hold the key?
por: Rinaldi, S.F., et al.
Publicado: (2015)

Increased Intraepithelial Vα24 Invariant NKT Cells in the Celiac Duodenum
por: Montalvillo, Enrique, et al.
Publicado: (2015)

CD1d Expression and Invariant NKT Cell Responses in Herpesvirus Infections
por: Chung, Brian K., et al.
Publicado: (2015)

Harnessing Invariant NKT Cells to Improve Influenza Vaccines: A Pig Perspective
por: Yang, Guan, et al.
Publicado: (2017)

SOX4 controls invariant NKT cell differentiation by tuning TCR signaling
por: Malhotra, Nidhi, et al.
Publicado: (2018)

Leishmania infantum Exoproducts Inhibit Human Invariant NKT Cell Expansion and Activation
por: Belo, Renata, et al.
Publicado: (2017)

Primary Mouse Invariant Natural Killer T (iNKT) Cell Purification and Transduction
por: Delfanti, Gloria, et al.
Publicado: (2023)

Regeneration of invariant natural killer T (iNKT) cells: application of iPSC technology for iNKT cell-targeted tumor immunotherapy
por: Aoki, Takahiro, et al.
Publicado: (2023)

Co-delivery of PLGA encapsulated invariant NKT cell agonist with antigenic protein induce strong T cell-mediated antitumor immune responses
por: Dölen, Yusuf, et al.
Publicado: (2015)

Novel lipid antigens for NKT cells in cancer
por: Lee, Michael S., et al.
Publicado: (2023)

The Response of CD1d-Restricted Invariant NKT Cells to Microbial Pathogens and Their Products
por: Van Kaer, Luc, et al.
Publicado: (2015)

Overexpression of RANKL by invariant NKT cells enriched in the bone marrow of patients with multiple myeloma
por: Spanoudakis, E, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_avcc681qicmi955d42f61l5bbl