Genome-wide association study of Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis in Europe

BACKGROUND: Stevens-Johnson syndrome (SJS) and Toxic Epidermal Necrolysis (TEN) are rare but extremely severe cutaneous adverse drug reactions in which drug-specific associations with HLA-B alleles were described. OBJECTIVES: To investigate genetic association at a genome-wide level on a large sampl...

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Detalles Bibliográficos
Autores principales: Génin, Emmanuelle, Schumacher, Martin, Roujeau, Jean-Claude, Naldi, Luigi, Liss, Yvonne, Kazma, Rémi, Sekula, Peggy, Hovnanian, Alain, Mockenhaupt, Maja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3173287/
https://www.ncbi.nlm.nih.gov/pubmed/21801394
http://dx.doi.org/10.1186/1750-1172-6-52

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