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Viral suppression of multiple escape mutants by de novo CD8(+ )T cell responses in a human immunodeficiency virus-1 Infected elite suppressor
Elite suppressors or controllers (ES) are HIV-1 infected patients who maintain undetectable viral loads without treatment. While HLA-B*57-positive ES are usually infected with virus that is unmutated at CTL epitopes, a single, dominant variant containing CTL escape mutations is typically seen in pla...
Autores principales: | O'Connell, Karen A, Hegarty, Robert W, Siliciano, Robert F, Blankson, Joel N |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3173334/ https://www.ncbi.nlm.nih.gov/pubmed/21812985 http://dx.doi.org/10.1186/1742-4690-8-63 |
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