A galU mutant of francisella tularensis is attenuated for virulence in a murine pulmonary model of tularemia

BACKGROUND: A number of studies have revealed that Francisella tularensis (FT) suppresses innate immune responses such as chemokine/cytokine production and neutrophil recruitment in the lungs following pulmonary infection via an unidentified mechanism. The ability of FT to evade early innate immune...

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Detalles Bibliográficos
Autores principales: Jayakar, Himangi R, Parvathareddy, Jyothi, Fitzpatrick, Elizabeth A, Bina, Xiaowen R, Bina, James E, Re, Fabio, Emery, Felicia D, Miller, Mark A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3173336/
https://www.ncbi.nlm.nih.gov/pubmed/21819572
http://dx.doi.org/10.1186/1471-2180-11-179

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