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Cigarette smoke extract upregulates heme oxygenase-1 via PKC/NADPH oxidase/ROS/PDGFR/PI3K/Akt pathway in mouse brain endothelial cells
BACKGROUND: In the brain, the inducible form of heme oxygenase (HO-1) has been recently demonstrated to exacerbate early brain injury produced by intracerebral hemorrhagic stroke which incident rate has been correlated with cigarette smoking previously. Interestingly, cigarette smoke (CS) or chemica...
Autores principales: | Shih, Ruey-Horng, Cheng, Shin-Ei, Hsiao, Li-Der, Kou, Yu Ru, Yang, Chuen-Mao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3173343/ https://www.ncbi.nlm.nih.gov/pubmed/21861928 http://dx.doi.org/10.1186/1742-2094-8-104 |
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