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Patterns, trends and sex differences in HIV/AIDS reported mortality in Latin American countries: 1996-2007

BACKGROUND: International cohort studies have shown that antiretroviral treatment (ART) has improved survival of HIV-infected individuals. National population based studies of HIV mortality exist in industrialized settings but few have been presented from developing countries. Our objective was to i...

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Autores principales: Alonso Gonzalez, Monica, Martin, Luise, Munoz, Sergio, Jacobson, Jerry O
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3173348/
https://www.ncbi.nlm.nih.gov/pubmed/21801402
http://dx.doi.org/10.1186/1471-2458-11-605
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author Alonso Gonzalez, Monica
Martin, Luise
Munoz, Sergio
Jacobson, Jerry O
author_facet Alonso Gonzalez, Monica
Martin, Luise
Munoz, Sergio
Jacobson, Jerry O
author_sort Alonso Gonzalez, Monica
collection PubMed
description BACKGROUND: International cohort studies have shown that antiretroviral treatment (ART) has improved survival of HIV-infected individuals. National population based studies of HIV mortality exist in industrialized settings but few have been presented from developing countries. Our objective was to investigate on a population basis, the regional situation regarding HIV mortality and trends in Latin America (LA) in the context of adoption of public ART policies and gender differences. METHODS: Cause of death data from vital statistics registries from 1996 to 2007 with "good" or "average" quality of mortality data were examined. Standardized mortality rates and Poisson regression models by country were developed and differences among countries assessed to identify patterns of HIV mortality over time occurring in Latin America. RESULTS: Standardized HIV mortality following the adoption of public ART policies was highest in Panama and El Salvador and lowest in Chile. During the study period, three overall patterns were identified in HIV mortality trends- following the adoption of the free ART public policies; a remarkable decrement, a remarkable increment and a slight increment. HIV mortality was consistently higher in males compared to females. Mean age of death attributable to HIV increased in the majority of countries over the study period. CONCLUSIONS: Vital statistics registries provide valuable information on HIV mortality in LA. While the introduction of national policies for free ART provision has coincided with declines in population-level HIV mortality and increasing age of death in some countries, in others HIV mortality has increased. Barriers to effective ART implementation and uptake in the context of free ART public provision policies should be further investigated.
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spelling pubmed-31733482011-09-15 Patterns, trends and sex differences in HIV/AIDS reported mortality in Latin American countries: 1996-2007 Alonso Gonzalez, Monica Martin, Luise Munoz, Sergio Jacobson, Jerry O BMC Public Health Research Article BACKGROUND: International cohort studies have shown that antiretroviral treatment (ART) has improved survival of HIV-infected individuals. National population based studies of HIV mortality exist in industrialized settings but few have been presented from developing countries. Our objective was to investigate on a population basis, the regional situation regarding HIV mortality and trends in Latin America (LA) in the context of adoption of public ART policies and gender differences. METHODS: Cause of death data from vital statistics registries from 1996 to 2007 with "good" or "average" quality of mortality data were examined. Standardized mortality rates and Poisson regression models by country were developed and differences among countries assessed to identify patterns of HIV mortality over time occurring in Latin America. RESULTS: Standardized HIV mortality following the adoption of public ART policies was highest in Panama and El Salvador and lowest in Chile. During the study period, three overall patterns were identified in HIV mortality trends- following the adoption of the free ART public policies; a remarkable decrement, a remarkable increment and a slight increment. HIV mortality was consistently higher in males compared to females. Mean age of death attributable to HIV increased in the majority of countries over the study period. CONCLUSIONS: Vital statistics registries provide valuable information on HIV mortality in LA. While the introduction of national policies for free ART provision has coincided with declines in population-level HIV mortality and increasing age of death in some countries, in others HIV mortality has increased. Barriers to effective ART implementation and uptake in the context of free ART public provision policies should be further investigated. BioMed Central 2011-07-29 /pmc/articles/PMC3173348/ /pubmed/21801402 http://dx.doi.org/10.1186/1471-2458-11-605 Text en Copyright ©2011 Alonso et al; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Alonso Gonzalez, Monica
Martin, Luise
Munoz, Sergio
Jacobson, Jerry O
Patterns, trends and sex differences in HIV/AIDS reported mortality in Latin American countries: 1996-2007
title Patterns, trends and sex differences in HIV/AIDS reported mortality in Latin American countries: 1996-2007
title_full Patterns, trends and sex differences in HIV/AIDS reported mortality in Latin American countries: 1996-2007
title_fullStr Patterns, trends and sex differences in HIV/AIDS reported mortality in Latin American countries: 1996-2007
title_full_unstemmed Patterns, trends and sex differences in HIV/AIDS reported mortality in Latin American countries: 1996-2007
title_short Patterns, trends and sex differences in HIV/AIDS reported mortality in Latin American countries: 1996-2007
title_sort patterns, trends and sex differences in hiv/aids reported mortality in latin american countries: 1996-2007
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3173348/
https://www.ncbi.nlm.nih.gov/pubmed/21801402
http://dx.doi.org/10.1186/1471-2458-11-605
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