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Autocrine activity of soluble Flt-1 controls endothelial cell function and angiogenesis

BACKGROUND: The negative feedback system is an important physiological regulatory mechanism controlling angiogenesis. Soluble vascular endothelial growth factor (VEGF) receptor-1 (sFlt-1), acts as a potent endogenous soluble inhibitor of VEGF- and placenta growth factor (PlGF)-mediated biological fu...

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Detalles Bibliográficos
Autores principales:	Ahmad, Shakil, Hewett, Peter W, Al-Ani, Bahjat, Sissaoui, Samir, Fujisawa, Takeshi, Cudmore, Melissa J, Ahmed, Asif
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2011
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3173355/ https://www.ncbi.nlm.nih.gov/pubmed/21752276 http://dx.doi.org/10.1186/2045-824X-3-15

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