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Twist and snai1 expression in pharyngeal squamous cell carcinoma stroma is related to cancer progression

BACKGROUND: Epithelial-mesenchymal transition (EMT) is a crucial process in tumorigenesis since tumor cells attain fibroblast-like features enabling them to invade to surrounding tissue. Two transcription factors, TWIST and SNAI1, are fundamental in regulating EMT. METHODS: Immunohistochemistry was...

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Detalles Bibliográficos
Autores principales: Jouppila-Mättö, Anna, Närkiö-Mäkelä, Mervi, Soini, Ylermi, Pukkila, Matti, Sironen, Reijo, Tuhkanen, Hanna, Mannermaa, Arto, Kosma, Veli-Matti
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3173446/
https://www.ncbi.nlm.nih.gov/pubmed/21834956
http://dx.doi.org/10.1186/1471-2407-11-350