Selective Recruitment of Regulatory T Cell through CCR6-CCL20 in Hepatocellular Carcinoma Fosters Tumor Progression and Predicts Poor Prognosis

BACKGROUND: Regulatory T cells (Tregs) are highly prevalent in tumor tissue and can suppress effective anti-tumor immune responses. However, the source of the increased tumor-infiltrating Tregs and their contribution to cancer progression remain poorly understood. METHODOLOGY/PRINCIPAL FINDING: We h...

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Detalles Bibliográficos
Autores principales: Chen, Kang-Jie, Lin, Sheng-Zhang, Zhou, Lin, Xie, Hai-Yang, Zhou, Wu-Hua, Taki-Eldin, Ahmed, Zheng, Shu-Sen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3173477/
https://www.ncbi.nlm.nih.gov/pubmed/21935436
http://dx.doi.org/10.1371/journal.pone.0024671

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