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Emerging Applications of Bacterial Spores in Nanobiotechnology

Bacterial spores are robust and dormant life forms with formidable resistance properties, in part, attributable to the multiple layers of protein that encase the spore in a protective and flexible shield. The coat has a number of features pertinent to the emerging field of nanobiotechnology includin...

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Detalles Bibliográficos
Autores principales: Ricca, Ezio, Cutting, Simon M
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2003
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC317360/
https://www.ncbi.nlm.nih.gov/pubmed/14675488
http://dx.doi.org/10.1186/1477-3155-1-6
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author Ricca, Ezio
Cutting, Simon M
author_facet Ricca, Ezio
Cutting, Simon M
author_sort Ricca, Ezio
collection PubMed
description Bacterial spores are robust and dormant life forms with formidable resistance properties, in part, attributable to the multiple layers of protein that encase the spore in a protective and flexible shield. The coat has a number of features pertinent to the emerging field of nanobiotechnology including self-assembling protomers and the capacity for engineering and delivery of foreign molecules. This review gives an account of recent progress describing the use of the spore, and specifically, the spore coat as a vehicle for heterologous antigen presentation and protective immunization (vaccination). As interest in the spore coat increases it seems likely that they will be exploited further for drug and enzyme delivery as well as a source of novel self-assembling proteins.
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spelling pubmed-3173602004-01-23 Emerging Applications of Bacterial Spores in Nanobiotechnology Ricca, Ezio Cutting, Simon M J Nanobiotechnology Review Bacterial spores are robust and dormant life forms with formidable resistance properties, in part, attributable to the multiple layers of protein that encase the spore in a protective and flexible shield. The coat has a number of features pertinent to the emerging field of nanobiotechnology including self-assembling protomers and the capacity for engineering and delivery of foreign molecules. This review gives an account of recent progress describing the use of the spore, and specifically, the spore coat as a vehicle for heterologous antigen presentation and protective immunization (vaccination). As interest in the spore coat increases it seems likely that they will be exploited further for drug and enzyme delivery as well as a source of novel self-assembling proteins. BioMed Central 2003-12-15 /pmc/articles/PMC317360/ /pubmed/14675488 http://dx.doi.org/10.1186/1477-3155-1-6 Text en Copyright © 2003 Ricca and Cutting; licensee BioMed Central Ltd. This is an Open Access article: verbatim copying and redistribution of this article are permitted in all media for any purpose, provided this notice is preserved along with the article's original URL.
spellingShingle Review
Ricca, Ezio
Cutting, Simon M
Emerging Applications of Bacterial Spores in Nanobiotechnology
title Emerging Applications of Bacterial Spores in Nanobiotechnology
title_full Emerging Applications of Bacterial Spores in Nanobiotechnology
title_fullStr Emerging Applications of Bacterial Spores in Nanobiotechnology
title_full_unstemmed Emerging Applications of Bacterial Spores in Nanobiotechnology
title_short Emerging Applications of Bacterial Spores in Nanobiotechnology
title_sort emerging applications of bacterial spores in nanobiotechnology
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC317360/
https://www.ncbi.nlm.nih.gov/pubmed/14675488
http://dx.doi.org/10.1186/1477-3155-1-6
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