The pharmacological effect of BGC20-1531, a novel prostanoid EP(4) receptor antagonist, in the Prostaglandin E(2) human model of headache

Using a human Prostaglandin E(2) (PGE(2)) model of headache, we examined whether a novel potent and selective EP(4) receptor antagonist, BGC20-1531, may prevent headache and dilatation of the middle cerebral (MCA) and superficial temporal artery (STA). In a three-way cross-over trial, eight healthy...

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Detalles Bibliográficos
Autores principales: Antonova, Maria, Wienecke, Troels, Maubach, Karen, Thomas, Emma, Olesen, Jes, Ashina, Messoud
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Milan 2011
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3173651/
https://www.ncbi.nlm.nih.gov/pubmed/21681585
http://dx.doi.org/10.1007/s10194-011-0358-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3173651/
https://www.ncbi.nlm.nih.gov/pubmed/21681585
http://dx.doi.org/10.1007/s10194-011-0358-9

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