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The pharmacological effect of BGC20-1531, a novel prostanoid EP(4) receptor antagonist, in the Prostaglandin E(2) human model of headache
Using a human Prostaglandin E(2) (PGE(2)) model of headache, we examined whether a novel potent and selective EP(4) receptor antagonist, BGC20-1531, may prevent headache and dilatation of the middle cerebral (MCA) and superficial temporal artery (STA). In a three-way cross-over trial, eight healthy...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer Milan
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3173651/ https://www.ncbi.nlm.nih.gov/pubmed/21681585 http://dx.doi.org/10.1007/s10194-011-0358-9 |