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Differential Effect of Calsequestrin Ablation on Structure and Function of Fast and Slow Skeletal Muscle Fibers
We compared structure and function of EDL and Soleus muscles in adult (4–6 m) mice lacking both Calsequestrin (CASQ) isoforms, the main SR Ca(2+)-binding proteins. Lack of CASQ induced ultrastructural alterations in ~30% of Soleus fibers, but not in EDL. Twitch time parameters were prolonged in both...
Autores principales: | Paolini, Cecilia, Quarta, Marco, D'Onofrio, Laura, Reggiani, Carlo, Protasi, Feliciano |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3173739/ https://www.ncbi.nlm.nih.gov/pubmed/21941434 http://dx.doi.org/10.1155/2011/634075 |
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