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The peroxisome proliferator activated receptor δ is required for the differentiation of THP-1 monocytic cells by phorbol ester

BACKGROUND: PPARδ (NR1C2) promotes lipid accumulation in human macrophages in vitro and has been implicated in the response of macrophages to vLDL. We have investigated the role of PPARδ in PMA-stimulated macrophage differentiation. The THP-1 monocytic cell line which displays macrophage like differ...

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Detalles Bibliográficos
Autores principales:	Vosper, Helen, Khoudoli, Guennadi A, Palmer, Colin NA
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2003
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC317379/ https://www.ncbi.nlm.nih.gov/pubmed/14670086 http://dx.doi.org/10.1186/1478-1336-1-9

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