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An Intracytoplasmic IL-10 Receptor Variant Permits Rapid Reduction in STAT3 Activation
Within the IL10R1 gene two common variants are associated with certain diseases: SNP3, a serine-138-to-glycine mutation is in linkage disequilibrium with SNP4, a glycine-330-to-arginine mutation, both of which are considered loss-of-function alleles. However, the molecular consequence of G330R is un...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3173877/ https://www.ncbi.nlm.nih.gov/pubmed/21654841 http://dx.doi.org/10.1038/gene.2011.12 |