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Wilson's disease: MRI features

A 15-year-old boy presented with coarse tremors of right hand and dysarthric speech. Neurologic examination demonstrated Kayser-Fleischer rings and dystonic tremor of the right hand. Serum ceruloplasmin and urine copper studies established the diagnosis of Wilson's disease. Brain MRI showed bil...

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Detalles Bibliográficos
Autores principales: Singh, Paramdeep, Ahluwalia, Archana, Saggar, Kavita, Grewal, Charanpreet Singh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3173909/
https://www.ncbi.nlm.nih.gov/pubmed/21977083
http://dx.doi.org/10.4103/1817-1745.84402
Descripción
Sumario:A 15-year-old boy presented with coarse tremors of right hand and dysarthric speech. Neurologic examination demonstrated Kayser-Fleischer rings and dystonic tremor of the right hand. Serum ceruloplasmin and urine copper studies established the diagnosis of Wilson's disease. Brain MRI showed bilateral T2 hyperintensity involving putamen, thalami, and brainstem. Involvement of brainstem revealed the characteristic “double panda sign.”