New inhibitors of VEGFR-2 targeting the extracellular domain dimerization process

We are reporting the discovery of small molecule inhibitors for vascular endothelial growth factor receptor type 2 (VEGFR-2) extracellular domain. The VEGFR-2 extracellular domain is responsible for the homo-dimerization process, which has been recently reported as a main step in VEGFR signal transd...

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Detalles Bibliográficos
Autores principales: ElGamacy, Mohammad Amin, Shalaby, Raed Ahmed, Elkodsh, Ahmad Tawfik, Kamel, Amr Fawzy, Elsayed, Mohamed Saad Abdullah, Abou-El-Ella, Dalal Abd El Rahman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Biomedical Informatics 2011
Materias:
Hypothesis
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3174036/
https://www.ncbi.nlm.nih.gov/pubmed/21938205

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