DDTRP: Database of Drug Targets for Resistant Pathogens

Emergence of drug resistance is a major threat to public health. Many pathogens have developed resistance to most of the existing antibiotics, and multidrug-resistant and extensively drug resistant strains are extremely difficult to treat. This has resulted in an urgent need for novel drugs. We desc...

Descripción completa

Detalles Bibliográficos
Autores principales: Sundaramurthi, Jagadish Chandrabose, Ramanandan, Prabhakaran, Brindha, Sridharan, Subhasree, Chelladurai Ramarathnam, Prasad, Abhimanyu, Kumaraswami, Vasanthapuram, Hanna, Luke Elizabeth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Biomedical Informatics 2011
Materias:
Database
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3174044/
https://www.ncbi.nlm.nih.gov/pubmed/21938213
Descripción
Sumario:Emergence of drug resistance is a major threat to public health. Many pathogens have developed resistance to most of the existing antibiotics, and multidrug-resistant and extensively drug resistant strains are extremely difficult to treat. This has resulted in an urgent need for novel drugs. We describe a database called ‘Database of Drug Targets for Resistant Pathogens’ (DDTRP). The database contains information on drugs with reported resistance, their respective targets, metabolic pathways involving these targets, and a list of potential alternate targets for seven pathogens. The database can be accessed freely at http://bmi.icmr.org.in/DDTRP.

Ejemplares similares